Sunday, December 23, 2012

Stem Cell News - December 23, 2012

New Source for Stem Cells: Dead People
Newser
(Newser) – Even after five days, corpses are an excellent source of stem cells to replace fat, cartilage, bone, and other kinds of cells, New Scientist reports. A research team from the University of Miami, Florida, found it could mine mesenchymal stem ...
Radical Stem Cell Treatment Saves Man's Sight
Mashable
The unknown disease affected the stem cells that keep the corneas in his eyes healthy. The deficiency causes excruciating pain and blurred vision. SEE ALSO: Where's the Beef? Scientists Turn Stem Cells into PETA-Approved Meat. Binns became the first ...
Stem cell facelift goes awry, woman grows bone in eyes
Newstrack India
One theory is the stem cells - which can develop into any tissue in the body - could have reacted with a common dermal filler which contains calcium. Stem cells are the building blocks of tissue growth. They can transform into any other type of cell ...
Iranian Scientists to Produce Human Organs through Supplementation of Stem ...
Fars News Agency
"In the new project of the Royan institute, we plan to produce human organs in the body of animals through supplementation of stem cells," Head of Royan Institute Mohammad Hossein Nasr Esfahani told FNA in the Central city of Isfahan on Sunday ...

Stem Cell Facelift Caused Bone Fragment Growing in Women Eye
Beauty World News
Plastic surgeons are now using stem cells to make women look years younger without the pain of an invasive surgery. According to Fox News, Aestetic Surgery using patients own adult stem cells can turn back the clock. Doctors believe the new technology ...


Stem Cells Treat Lou Gehrig's Disease, In Mice
NPR
Reporting in Science Translational Medicine, researchers write that neural stem cell implants were able to slow the onset of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, in mice. Study author Evan Snyder discusses the stem cells ...
Cadaver stem cells offer new hope of life after death
New Scientist
Dead bodies can provide organs for transplants, now they might become a source of stem cells too. Huge numbers of stem cells can still be mined from bone marrow five days after death to be potentially used in a variety of life-saving treatments. Human ...
Stem cells on path to rebuild blood 'pipeline'
Futurity: Research News
(Credit: Cheng-Tao Yang via Competitions @ OUCS/Flickr). JOHNS HOPKINS (US) — Engineers can now prod stem cells to help build vein and artery networks, overcoming a stumbling block to growing replacement blood vessels in the laboratory. Tweet ...
Ontario man's sight restored with help of stem cells
CTV News
When Taylor Binns slowly began going blind because of complications with his contact lenses, he started to prepare for living the rest of his life without vision. But an innovative treatment using stem cells has changed all that, and returned to him ...
Egg production from stem cells among top 10 Science achievements
The Japan Times
Kyodo. The U.S. magazine Science chose the achievement by Japanese researchers to produce eggs from artificially derived multipurpose stem cells as one of the top 10 scientific breakthroughs of 2012, the journal said in its issue out Friday.
Woman's Plastic Surgery for Saggy Eyelids Has Horrifyingly Unexpected Side ...
The Stir (blog)
Except this particular woman, who lives in Los Angeles, had a non-FDA-approved cosmetic eye surgery using stem cells. Because this type of cosmetic surgery doesn't actually require FDA approval, so this type of cosmetic surgery doesn't actually require ...

Why Stem Cell Facelifts Are So Risky
LiveScience.com
The bone fragments and swelling were the result of a botched facelift the woman had received three months earlier from a different doctor: He injected stem cells derived from the woman's abdominal fat directly into the area around her eyes. Apparently ...
Botched stem cell facelift leaves woman with bones growing in her EYES
Daily Mail
One theory is the stem cells – which can develop into any tissue in the body – could have reacted with a common dermal filler which contains calcium. The procedure the woman had is unregulated in America. It involves removing the patient's stem cells ...

At the Heart of Genetic Shenanigans
dailyRx
Scientists may have discovered a way to contain wayward and chaotic stem cells that can keep CML active. In this animal study, a protein was identified that seems to be at the heart of CML. Blocking this molecule – RAD52 – in mice disabled CML cells so ...
See all stories on this topic »
OncoMed Pharmaceuticals Initiates Phase 1 Clinical Trial of Anti-Cancer Stem ...
PharmaLive (press release) (subscription)
(BUSINESS WIRE)--Dec 21, 2012 - OncoMed Pharmaceuticals, Inc., a clinical-stage company developing novel therapeutics that target cancer stem cells (CSCs), or tumor-initiating cells, today announced that patient dosing has begun in a Phase 1 clinical ...
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Korea Advances Organ Transplants with Stem Cell Therapy
Arirang News
These special stem cells ensure that the receiving patent's immune system adapts or is even replaced to ensure that the new kidney is accepted by the body without complications. [Interview : Dr. Kim Hee-je, Hematopoietic Transplantation Center Seoul St.
Cal-X Stars Accelerator to Present Medtech Portfolio at Founders Club During ...
eReleases (press release)
MyoStim Pacers – www.myostimpacers.com – First heart pacemaker designed to recruit healing stem cells to heart tissue and to promote proliferation of resident cardiomyocytes and new blood vessel growth. A peripheral model is designed to accelerate ...


Steering Stem Cells to Become Two Different Building Blocks for New Blood ...
Science Daily (press release)
Dec. 20, 2012 — Growing new blood vessels in the lab is a tough challenge, but a Johns Hopkins engineering team has solved a major stumbling block: how to prod stem cells to become two different types of tissue that are needed to build tiny networks ...»
Breakthrough on breast cancer stem cells
The Australian
Researchers from Griffith University and the Queensland Institute of Medical Research (QIMR) are working towards making breast cancer stem cells the target of specific cancer therapies, to improve treatment outcomes. "We have described a method to ...
Science: Wrinkle Treatment Using Stem Cells Causes Bones to Grow in ...
National Review Online (blog)
Let it be said that stem cell therapies may well be the future of medicine, but untested stem cell therapies have the potential to give rise to the stuff of nightmares. Case in point: the unnamed cosmetic surgery patient in this piece by SciAm's Ferris ...

Implications of long-term culture for mesenchymal stem cells: genetic defects ...
7thSpace Interactive (press release)
Mesenchymal stem cells change dramatically during culture expansion. Long-term culture has been suspected to evoke oncogenic transformation: overall, the genome appears to be relatively stable throughout culture but transient clonal aneuploidies have ...
Woman Who Had Cosmetic Stem Cell Treatment Grew Bones In Her Eye
Uproxx
The difficulty started three months earlier, when she underwent a $20,000+ cosmetic procedure at a Beverly Hills clinic. The procedure was a face-lift combined with injections of her own stem cells. Three months later, she's in pain and her eye's ...

Protein kinase Akt identified as arbiter of cancer stem cell fate, paper reports
Medical Xpress
Signaling via the Akt serine/threonine protein kinase plays critical roles in the self-renewal of embryonic stem cells and their malignant counterpart, embryonal carcinoma cells. Credit: Honglin Zhou, Perelman School of Medicine, University of ...
Adventures of the 1%: Woman Gets $20K Facial, Grows Bones In Her Eye Socket
Refinery29 (blog)
According to a report published in Scientific American, the very-scientific-sounding stem cell facial was administered by a cosmetic surgeon who "removed abdominal fat cells with liposuction and isolated the adult stem cells within — a family of cells ...

Stem Cell Research Shows ALS May Be Treatable
Laboratory Equipment
A decade of research conducted at multiple institutions, shows that when neural stem cells were transplanted into multi-levels of the spinal cord of a mouse model with familial ALS, disease onset and progression slowed, motor and breathing function ...
Stemedica Issued US Patent For Stem Cell Treatment of Diabetic Retinopathy ...
San Francisco Chronicle (press release)
This broad-based patent covers the treatment of diabetic retinopathy and other degenerative diseases of the eye with the Company's ischemic tolerant neural (itNSC) and mesenchymal (itMSC) stem cells. San Diego, CA (PRWEB) December 20, 2012 ...
Hemp, Inc. Announces BioSwan, Inc. -- An Update On One Of Its Spinoffs
Daily Markets (press release)
While our research uncovered the valuable herbal blends that increase the specific stem cells, it is outside of Hemp's core business and detracts from the management team's ability to focus. By spinning it off, the shareholders receive stock in BioSwan ...
Unapproved cosmetic surgery leaves woman with bone fragments in eye
Fox News
The procedure was a stem-cell face-lift, where doctors took adult stem cells from her stomach fat and after isolating them and injecting them the filler calcium hydroxylapatite, shot them around her eyes. The woman paid more than $20,000 to have the ...
Bones Get in Her Eyes
Scientist
After undergoing untested cosmetic surgery that uses stem cells to rejuvenate skin, a woman grew bone fragments in the flesh around one of her eyes. By Dan Cossins | December 20, 2012. Comments. WIKIMEDIA, 8THSTARA Los Angeles woman who opted ...

New study investigates fate and function of cells transplanted to the CNS
Medical Xpress
A Belgian research team carried out research aimed at answering this question by determining how five varieties of cells - neural stem cells, mouse embryonic fibroblasts, dendritic cells, bone marrow mononuclear cells (BMMNCs) and splenocytes ...
Transplanted Neural Stem Cells Treat Amyotrophic Lateral Sclerosis in Mouse ...
Science Daily (press release)
Surprisingly, the transplanted neural stem cells did not benefit ALS mice by replacing deteriorating nerve cells. Instead, neural stem cells help by producing factors that preserve the health and function of the host's remaining nerve cells. They also ...
Upstate and two other medical schools hope to use stem cells to fight multiple ...
Syracuse.com
Syracuse, N.Y. -- Upstate Medical University and two other New York medical schools hope to implant stem cells into multiple sclerosis patients to reverse some of their symptoms and slow the progression of the often disabling disease. The Empire State ...
Woman undergoes untested stem-cell wrinkle treatment, sprouts bones in her ...
io9
Case in point: the unnamed cosmetic surgery patient in this piece by SciAm's Ferris Jabr, who, after dropping 20 grand on an untested, non-FDA-approved facelift that made use of her own stem cells, grew some extra bones in her face. In her eyelid, to ...
Stem cells from umbilical cord could cure leukemia girl
KSWT-TV
Los Algodones, Mexico--According to Dr. Jose Luis Diaz barboza he is no longer fighting Emily Bracamontes cancer with chemotherapy. He is administering growth factors to help increase her blood cell count. But saving Emily's life could come down to ...
Myelofibrosis stem cells may exist in spleens of patients
Healio
Myelofibrosis stem cells in the spleens of patients with this disease may retain differentiation programs identical to those found in normal hematopoietic stem cells, according to study results. The researchers conducted the study to evaluate the ...
Protein Kinase Akt Identified as Arbiter of Cancer Stem Cell Fate, According ...
HealthCanal.com
This new research shows that Akt may be the key as to why cancer stem cells are so hard for the body to get rid of. It has been documented that frequent hyperactivation of Akt kinases occurs in many types of human solid tumors and blood malignancies.
2013 Smart Guide: Revolutionary human stem cell trial
New Scientist
He called these cells induced pluripotent stem cells. iPSCs can grow into any tissue in the body by exposure to natural growth factors. The long-term goal of the pioneering trial of iPSC-derived cells is to provide blood platelets to people undergoing ...
Trials soon to test treatment for blindness due to chemical burns
The Hindu
He was referring to the Simple Limbal Epithelial Transplantation (SLET), where the limbal stem cells harvested from the healthy eye are allowed to grow in the damaged eye thereby restoring corneal transparency. The technique was developed jointly by Dr.

Umbilical cord stem cell therapy shows promise in infant BPD
News-Medical.net
Researchers have successfully used human umbilical cord stem cells to partially prevent damage and restore lung structure and function in an experimental animal model of bronchopulmonary dysplasia (BPD). "BPD is a lung disease described 45 years ago ...
Nobel Prize Winner Says Human Cloning Coming Within 50 Years
LifeNews.com
Those of us who could read between the lines have always known that so-called therapeutic cloning, the creation and cloned human embryos with somatic cell nuclear transfer (SCNT) and their subsequent destruction for stem cells, has always ultimately ...
Induced "pacemaker" heart cells could take the place of man-made pacemakers
Gizmag
Pacemaker cells have also been created from embryonic stem cells, although using such cells could introduce a risk of cancer. “Although we and others have created primitive biological pacemakers before, this study is the first to show that a single ...
How Airway Cells Regenerate After Chlorine Gas Injury
Science Daily (press release)
Following chlorine-related injury, Hoyle found that a type of epithelial cells called basal cells initiated the repair and served as progenitor cells -- early descendants of stem cells that can differentiate to form one or more cell types. The ...

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